Studies on 5-8 Fused Ring Compounds. V. The Conformations of Eight-Membered Rings in 5-8-5 Fused Ring Compounds and Their cis-trans Isomerization
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چکیده
منابع مشابه
Synthesis and antitumor activity of duocarmycin derivatives: a-ring pyrrole compounds bearing 5-membered heteroarylacryloyl groups.
A series of A-ring pyrrole compounds of duocarmycin bearing 5-membered heteroarylacryloyl groups (thienylacryloyl and pyrrolylacryloyl) and heteroarylcarbonyl groups were synthesized and evaluated for in vitro anticellular activity against HeLa S3 cells and in vivo antitumor activity against murine sarcoma 180 in mice. Most of the thienylacrylates displayed in vitro anticellular activity equiva...
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The (5+2) cycloaddition reaction utilising cycloalkenes is rare, although it is one of the most efficient methods of constructing seven-membered fused rings because of its high atom- and step-economy. In this study, we used quantum mechanical calculations to predict the plausibility of using the Rh-catalysed intermolecular (5+2) cycloaddition of 3-acyloxy-1,4-enynes and cycloalkenes to produce ...
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ژورنال
عنوان ژورنال: Bulletin of the Chemical Society of Japan
سال: 1990
ISSN: 0009-2673,1348-0634
DOI: 10.1246/bcsj.63.2002